Scientific Officer - 3D cell culture facility

14/01/2018, 23:55

Breast Cancer Research
Directorate Breast Cancer Research
Full time
Fixed Term
2 years
35 hours
£25,400 - £28,325 inclusive based on relevance of skills and experience
The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment. Under the leadership of our Chief Executive, Professor Paul Workman FRS, the ICR is ranked as the UK’s leading academic research centre. Together with our partner The Royal Marsden, we are rated in the top five cancer centres globally.

The Breast Cancer Now Toby Robins Research Centre at the ICR, led by Professor Andrew Tutt, is the first centre in the UK entirely devoted to breast cancer research and its goal is to advance research into the causes, diagnosis and treatment of breast cancer. Formerly known as The Breakthrough Toby Robins Breast Cancer Research Centre, at The Institute of Cancer Research, London, it is located in state-of-the-art laboratory space, with excellent core facilities and funding. The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.

We are seeking an individual to form part of an exciting new initiative, to enable the development of models of patient tumour tissue from diagnosis and through treatment. The newly formed patient-derived organoid (PDO) facility is within the Breast Cancer Now Research Centre (BCNRC). This facility will provide expertise and support experiment design for the Centre, to enable these PDO models to be utilized with the aim of growing patient derived tumour tissue for translational studies. 3D cell culture and high content imaging, in combination with an unbiased informatics-based analysis, allows for an ex vivo approach to acquire a multi-parametric quantitative description of an in vitro 3D tumour phenotype. The appointed individual will join the PDO cell culture facility team in the BCNRC. As part of the team, he/she will work under the supervision of Dr Eleanor Knight, currently running and managing the facility, and will assist with developing, optimizing and carrying out complex 3D cell culture experiments with group members within the Centre.


The post will be based in the ICR, Chelsea. On occasion, appointed candidate will also interact with Professor Tutt’s laboratory at King’s College London (KCL).


Applicants should have a BSc in biological sciences and previous experience in primary cell culture, and/or methods of 3D cell culture and biochemical and/or immunohistochemical analysis technologies. Knowledge of breast cancer cell line models is advantageous. The post-holder will demonstrate good interpersonal skills and collaborative working practices. Excellent organizational and communication skills are essential.


Appointment will be on a Fixed Term Contract for 2 years in the first instance, with a salary in the range of £25,400 - £28,325 inclusive based on relevance of skills and experience.   


Informal enquiries are welcome and can be made to Dr. Inês Baptista (


Please do not send your application to Dr Baptista, formal applications must be submitted online. 

We consider all applications on merit and have a strong commitment to enhancing the diversity of our staff.

Funded by

Breast Cancer Now
Additional Documentation for Candidates

This Program is closed to applications.