Senior Program Manager in Cancer Genetics

17/06/2019, 23:55

Genetics and Epidemiology
Molecular & Population Genetics
Full time
Fixed Term
2 years in first instance, with extension to 5 years pending review
The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, we lead the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment. Together with our partner The Royal Marsden, we are rated in the top five cancer centres globally.

The Institute of Cancer Research (ICR) is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.

We are seeking a Senior Program Manager to work with us on delivery of our recently awarded £4.3 million CRUK Catalyst Award: “CanGene CanVar: Data Resources, Clinical and Educational Tools to leverage Cancer Susceptibility Genetics for Early Detection and Prevention of Cancer”, running 2019-2024. This large program is designed to deliver research and resources that will improve how we deliver national NHS testing for cancer susceptibility genes such as BRCA1, BRCA2 and genes for Lynch Syndrome.  It will involve working with a large team of scientists, clinicians and patients highly passionate about achieving this goal.

This complex program of work involves 16 PIs from seven Higher Education Institutes (ICR, Cambridge, Southampton, Manchester, Leeds, Oxford and St George’s University London) as well as Public Health England (Health Data Insight).  Components span from (i) complex linkage of routinely collected national datasets to inform research insights to (ii) de novo research including development of novel machine learning methodologies through to (iii) delivery and practical implementation within clinical and laboratory services in the NHS of tools, resources and guidelines.   

The program is structured into six inter-related Work-Packages:

1: Collection, linkage and analyses of nationally-collected genomic and cancer data

2:Data Clinical Laboratory Resources for Genomic Cancer Variant Interpretation

3:Dynamic Evidence-based Guidance for Clinical Geneticists, Oncologists and GPs

4:Patient-facing tools for decision-making and understanding risk

5:Medical Education

6:Ethics, Governance and Policy

Professor Dame Sue Hill and Ellen Graham from NHS England are named collaborators on the award on behalf of the NHS Genomic Medicine Service and we shall be working closely to coordinate national working groups. Delivery of the educational component will be in collaboration with Health Education England; Dr Anneke Sellars from the Genomics Education Program is likewise a named collaborator.  There are also over 40 additional collaborators on the Program, involving international researchers, NHS clinical geneticists, genetic counsellors, clinical scientists, oncologists and GPs, commercial partners and a PPI group comprising representation from various relevant patient groups.

We are seeking an individual with an exceptional track-record in management of complex scientific programs, in particular those (i) of a highly translational NHS-facing nature and/or (ii) involving coordination of software development.   We would anticipate that the successful candidate would have a background in biomedical science and a strong interest in cancer prevention, genomics, and health service implementation/transformation.

The postholder will assist in appointment of a full time administrative assistant/project manager and a junior post-doctoral researcher/project manager, together forming the program management team, which the postholder will lead.  The program management team will be responsible for (i) coordination and delivery of Work-Package milestones including coordination between co-investigators/collaborators and management of inter-dependencies, (ii) organization of all program meetings, (iii) liaison with CRUK including contracts and comms (iv) interaction with the finance departments of ICR and other bodies for management and reporting of program funds (v) program media and social media.

The postholder will report to Turnbull (at least) weekly, to the program Executive Committee (Clare Turnbull, Marc Tischkowitz and Diana Eccles) monthly, to the Management committee (all workpackage leads) quarterly and to the program Steering Group (all workpackage leads plus CRUK and PPI rep) six-monthly.

The post will be located at ICR Sutton, where several of the other program clinical and scientific appointees/students will be located.  Occasional UK travel may be required. For the right candidate, we are very open to flexible daily/weekly work-patterns including part-time working.

The post will be situated within the Division of Genetic and Epidemiology in the laboratory of Professors Clare Turnbull and Richard Houlston FRS, which comprises 20-25 post-doctoral scientists, bioinformaticians and students involved in a range of projects relating to Cancer Genomics.  A well as leading on delivery of this CRUK Catalyst Program, Professor Turnbull also undertakes a range of clinically-focused research work on susceptibility, somatic and functional cancer genomics.

Informal enquiries are welcome and can be made to Professor Clare Turnbull ( Please note – this address is for enquiries only and applications must be submitted via the apply button below.

We consider all applications on merit and have a strong commitment to enhancing the diversity of our staff.

Funded by

Cancer Research UK
Additional Documentation for Candidates

This Program is closed to applications.