Scientific Officer in Cancer Biology
Under the leadership of our Chief Executive, Professor Paul Workman FRS, the ICR is ranked as the UK’s leading academic research centre. Together with our partner The Royal Marsden, we are rated in the top four cancer centres globally.
The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.
A Scientific Officer post is available in the Development and Cancer Team as part of a 3-year project funded by Prostate Cancer UK to develop genetically modified 3 D models of prostate cancer. The aim is to use state of the art genome engineering technology to generate organoids, mini 3D organ derived structures, with genetic aberrations that mimic those found in prostate cancer patients. These novel 3D models will be used to understand the effect of aberrations on tumour biology and to study their response to therapies with the aim of identifying more effective treatments for this disease. The post holder will be assisting in the establishment of the workflow for genetic modification using CRISPR/Cas9 based technology of human and mouse primary cells and the phenotypic and drug sensitivity analyses of the 3D models. A working knowledge of tissue culture and molecular biology techniques is essential as are good organisational skills and the ability to work within a team. A background of 3D cell culture modelling and/or genetic modification techniques would be an advantage.
All applications should be submitted online via ICR recruitment system. When applying please provide a supporting statement as to why you are applying for this position and detailing your relevant experience.
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