Postdoctoral Training Fellow in Cancer Biology

29/02/2020, 23:55

Structural Biology
Vannini Group
Full time
Fixed Term
Until 30 June 2022
£32,200 - £39,350
The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment.

Under the leadership of our Chief Executive, Professor Paul Workman FRS, the ICR is ranked as the UK’s leading academic research centre. Together with our partner The Royal Marsden, we are rated in the top five cancer centres globally.

The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.

Funded by a 6-year Programme Foundation Award from Cancer Research UK, a post-doctoral position is available immediately in the laboratory of Dr. Alessandro Vannini, Division of Structural Biology at The Institute of Cancer Research in London. Working, in collaboration with Dr. Barrie Peck, Centre for Tumour Biology at the Barts Cancer Institute in London, we are looking for highly motivated and creative individuals with a strong interest in cancer biology, particularly functional genomics. We currently employ molecular and cell biology approaches in vitro and in vivo, to elucidate the role of the RNA Polymerase III transcription apparatus in cancer.

This is an ideal opportunity for a committed and enthusiastic scientist to join an established and dynamic research team with excellent collaborators and facilities. The Postdoctoral Researcher will work independently and take intellectual ownership of the project, while also working collaboratively with a higher scientific officer in order to deliver the research plan aimed at uncovering the role of RNA Polymerase III in cancer at the cellular and molecular level and exploit its therapeutic potential (see for example “Gouge et al., Cell 2015”).

Applicants should possess a PhD (or equivalent) in cell biology or related disciplines and should be familiar with multiple of the following techniques: functional genomics via next generation sequencing, genome editing with CRISPR, 3D cell culture, tissue culture/engineering and functional assays (such as FACS, growth and imaging assays).

Appointment will be on Fixed Term Contract until 30 June 2022 in the first instance, with a starting salary in the range of £32,200* to £39,350 p.a. inclusive (based on previous post-doctoral experience, *£32,200 starting salary is for pre-viva candidates).

Informal enquiries are welcome and can be made to Dr. Alessandro Vannini ( Please note, this address is for enquiries only and you should not send your application to this email address.

Application form, CV and supporting statement must be submitted online.

We reserve the right to close the advert before the published closing date once we have received a sufficient number of applications.  Therefore we advise to submit your application, as early as possible to avoid disappointment.

Previous applicants for this post need not to apply.

We consider all applications on merit and have a strong commitment to enhancing the diversity of our staff.

Funded by

Cancer Research UK
Additional Documentation for Candidates